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Opportunities to Reduce Obesity-Related Cancer Risk: GLP-1 Medications

Meeting Overview

Obesity is one of the most important modifiable drivers of cancer risk in the United States. It’s a complex chronic health condition that affects about 40% of U.S. adults and 20% of U.S. youth. Despite growing knowledge of obesity’s relationship to cancer, approaches to help Americans reach and maintain a healthy weight have failed to address the problem. Recent scientific advancements, including GLP-1 medications, present new opportunities to reduce obesity—and obesity-related cancer risk—at the population level.

The President’s Cancer Panel held a public meeting on obesity, cancer risk, and GLP-1 medications on October 15, 2026. The Panel convened experts to discuss biological mechanisms linking obesity to cancer and explore the possibility of harnessing GLP-1 medications for cancer prevention.

Event Details

Date and Time: October 15, 2026 | 9:00 a.m.–1:00 p.m. ET

Location: Online

Agenda

Time (EDT)Session
9:00–9:15 a.m.Opening Remarks & Introductions
9:15–10:15 a.m.

Session 1: Obesity and Cancer: The Role of GLP-1 Medications

Obesity, Metabolism, and Cancer: Biological Mechanisms and the Promise of Metabolic Therapies
Neil M. Iyengar, MD

Real World Evidence on GLP-1 Receptor Agonists: Insights into Cancer Outcomes
Serena Jingchuan Guo, MD, PhD

The Potential of GLP-1–Based Therapies for Cancer Prevention
Elizabeth McDonald, MD, PhD, FSBI

10:15–10:30 a.m.Break
10:30–11:30 a.m.

Session 2: Harnessing GLP-1 Medications for Cancer Prevention: Policy and Public Health Implications

Delivering Comprehensive GLP-1 Obesity Care in Primary Care
Melanie Jay, MD, MS

Understanding GLP-1 Medication Adoption and Access: Evolving Value, Affordability, and Coverage
David Kim, PhD

Informational Overview: Medicare GLP-1 Bridge Demonstration
Aurelia Chaudhury

11:30 a.m.–12:50 p.m.Discussion
12:50–1:00 p.m.Closing Remarks and Adjourn

Speakers

NameAffiliation
Victoria Bae-Jump, MD, PhD
Professor and Associate Division Director of Gynecologic Oncology
Director, UNC Lineberger Endometrial Cancer Center of Excellence
University of North Carolina at Chapel Hill
Chapel Hill, NC
Aurelia Chaudhury
Technical Advisor, Division of Drug Innovation, CMS Innovation Center
Centers for Medicare & Medicaid Services
Woodlawn, MD
Serena Jingchuan Guo, MD, PhD
William S. Bucke Associate Professor, Department of Pharmacy Practice
AI Director, College of Pharmacy
Purdue University
Investigator, Regenstrief Institute
Purdue Faculty Lead, Regenstrief Data Services
Indianapolis, IN
Neil M. Iyengar, MD
Section Chief, Breast Medical Oncology
Director, Cancer Survivorship Services
Associate Professor of Hematology and Medical Oncology
Winship Cancer Institute of Emory University
Atlanta, GA
Melanie Jay, MD, MS
Professor of Medicine and Population Health, NYU Grossman School of Medicine
Director, NYU Langone Comprehensive Program on Obesity Research
Director, Research Collaboration and Mentorship, Division of General Internal Medicine, NYU Langone Health
Director, VETCARE Center of Innovation, VA New York Harbor
New York, NY
David Kim, PhD
Associate Professor of Medicine
University of Chicago
Chicago, IL
Elizabeth McDonald, MD, PhD, FSBI
Professor of Radiology and Director of Breast MRI, Penn Medicine
Associate Vice-Chair for Research
University of Pennsylvania
Chair, American College of Radiology Breast Research Commission
Philadelphia, PA
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